Vacaise disease: symptoms, causes and features of treatment
If a person has high hemoglobin and overestimated red blood cell counts in the blood, then by no means can it be said that he is healthy. Unfortunately, these indicators are the first signs of Vacaise's disease. There are also a number of other symptoms that you should definitely pay attention to and immediately consult a specialist. In addition, it will be useful to find out other information about the pathology, which will help to identify this ailment in time and begin its treatment.
Vaquez disease (also called true or primary polycythemia) is a chronic tumor pathology that develops in the human circulatory system. As a rule, it is possible to identify this ailment due to diagnostic studies, during which it turns out that the level of red blood cells in the patient's blood is too much increased.However, in this case, the patients do not show any damage to the internal organs, in which such indicators are considered normal.
Also, with the development of Vaisez disease, the structure of the blood becomes more viscous and thick. Against this background, there is a strong slowdown in blood flow, which is why blood clots are not excluded. Such a condition can provoke hypoxia.
If we talk about the history of Vacaise, then it was first described in 1892. Then one scientist discovered the relationship between some patient indicators and the development of erythremia. Subsequently, the disease was named after the specialist himself. Therefore, in medical reference books, this pathology is more often known as the Vakeza Osler disease.
If we talk about who is most susceptible to this disease, then with the greatest caution to their health should be treated people of old age. Most often men suffer from polycythemia. Children and middle-aged people are much less likely to experience this disease. However, if the younger signs of an illness are detected in the younger generation, then in this case, Vaisez's disease is much more difficult.
What happens to the body when the disease
During true polycythemia, the volume of red blood cells in a person’s blood begins to increase greatly. Every day the patient's condition worsens. Against this background, leukocytosis and thrombocytosis begin to develop. Such processes of the pathological type increase blood viscosity, which leads to a significant increase in its volume. The movement of vital fluid slows down dramatically. The tissues of the human body no longer receive the required amount of oxygen.
Considering the pathogenesis of the Vaisez disease, it is worth considering that in some situations at the initial stage of development of the disease, the body begins to use compensatory mechanisms on its own. However, its protective functions are not enough for a long time, even if the person is famous for excellent immunity.
If the patient does not receive the appropriate treatment, then, according to the pathophysiology data, Vázez’s disease will begin to show itself more aggressively. After some time, the patient will have serious problems with high blood pressure. The spleen and liver can increase significantly. In an advanced degree, this pathology leads to disruption of the kidneys.
Against this background, the blood supply to the human heart and brain slows down significantly, and the limbs cease to function normally.
If a person does not take any measures for treatment, then the illness can even develop into a malignant true polycythemia. Vacaise disease is very dangerous, but this does not mean that patients should put a cross on themselves.
Causes of polycythemia
It is difficult to say about specific factors that lead to the development of pathology. This disease is still being studied by medical professionals. However, the etiology and pathogenesis of Varez's disease contain information that the disease develops against the background of mutational changes. They occur in stem cells located in the bone marrow. Accordingly, we are talking about genetic pathology.
Very often, several relatives have the same form of erythremia. Vaquez disease also develops on the background of enhanced erythropoiesis. As a rule, absolute erythrocytosis leads to it.
Also provoke a similar condition may be disorders associated with blood coagulation.However, experts allow other causes of pathology.
Is this a cancer disease?
Many patients, upon hearing that pathology belongs to the category of leukemias, begin to panic and associate it with blood cancer. However, this assumption is not entirely true. First of all, it is worth mentioning the malignant and benign nature of such an education. As a rule, if we are talking about cancer, in this case, doctors talk about the tumor, which consists of epithelial tissues. However, polycythemia (Vaisez disease) is a formation consisting of hematopoietic tissue. Nevertheless, the disease can still be attributed to malignant tumors.
However, it must be borne in mind that this pathology is characterized by a high differentiation of cells. In this case, there is a strong difference from cancer. The fact is that this disease for a very long time may be in a chronic stage. This means that the tumor is qualified as benign. If the treatment of Vaisez disease is done in a timely manner, then there is every chance of a full recovery.
If we allow the last stage of development of the disease, then in this case we will speak about a real malignant tumor. Therefore, it is better not to risk it.
At the initial stage of development, pathology is quite difficult to identify. Even if patients have any unpleasant sensations, rarely such a worsening state of health is most often associated with polycythemia. However, with the progression of the disease, the clinical picture becomes more pronounced, and doctors note the obvious features of the manifestation of Vaisez disease.
With the development of polycythemia:
- Hypodermic veins expand and swell. Skin may take on a reddish or bluish tinge. This is the main sign that the outflow of blood slowed down significantly and the vessels began to overflow with fluid.
- There is a violation of microcirculation of blood in the brain. In this case, patients complain of severe headaches, weakness, dizziness. It becomes very difficult for them to concentrate. Many have noted problems with vision and hearing.
- Arterial hypertension appears.
- Itching of the skin begins. It is noteworthy that itchy discomfort appears in the process of contact.skin with warm water. This means that when you take a shower or bath, the person feels the greatest discomfort.
- There are pain in the limbs.
- There are pains in the joints resembling gout.
- Ulcerative pathologies develop in the stomach and duodenum.
In addition, the formation of blood clots is often referred to as symptoms of Vázez’s disease. Therefore, do not close your eyes to such manifestations.
Stages of development of the disease
Since polycythemia in the first stages practically does not manifest in any way, all the symptoms described above occur only with more serious development of pathology. This disease is usually divided into three stages.
At the first stage, doctors note the satisfactory state of health of the patient. For erythremia (Vaisez disease) is characterized by the absence of pronounced symptoms. This stage can last about 5 years. During this time, neither the doctors nor the patient himself can even guess that he suffers from this dangerous disease.
After this comes the second stage, which is characterized by extensive clinical manifestations. It is divided into 2 categories. In the first case, doctors do not mark the spleen metaplasia.However, some patients pay attention to the appearance of some symptoms characteristic of erythremia. This stage can develop over 15 years.
There is also a second category 2 stage of pathology. In this case, the development of spleen metaplasia. Symptoms begin to appear more clearly. Most physicians pay attention to a significant increase in the size of the liver and spleen.
After this comes the 3rd stage. This stage of development of pathology is also called terminal. Patients are found almost all the symptoms of the fact that they suffer from a malignant process in the body. In this case, patients often claim that they hurt almost the entire body. This is explained by the fact that during the thermal stage of pathology, the cells of the human body no longer differentiate, which is why a substrate of leukemia is created. In this case, we are not talking about chronic erythremia.
During the terminal stage, there is a very serious condition of the patients. Some have ruptures of the spleen, infectious and inflammatory processes occur in the body, and hemorrhagic syndrome may develop.Also, certain groups of patients show immunodeficiency. Treatment of the disease is greatly complicated. If the pathology was brought to the final stage, then there is a big risk that it will end in death.
Is it possible to live with ailment
You need to understand that life expectancy with a diagnosis can be up to 20 years. If a patient has a disease in 60-80 years, then he may well not take any measures and continue a normal existence.
However, it all depends on the individual and the state of his body. In some situations, even in the early stages of polycythemia, the symptoms become pronounced. Because of this, it is much harder for a person to overlook an illness.
This pathology is quite easily detected if the doctor performs a general and biochemical blood test. Vaquez disease is found due to the increased volume of red blood cells and hemoglobin. At the same time, hematocrit indicators can reach up to 65% and more. Among the additional indicators worth noting the increased concentration of uric acid. Also, with Vaquez's disease, a blood test will show an increased volume of young red blood cells.
However, in some situations, experts doubt the accuracy of the diagnosis. To make sure that the person really suffers from polycythemia, it is necessary to make a puncture of the brain. If there is a suspicion that the disease was genetically transmitted, an appropriate blood test will be required.
Additionally, the doctor needs to clarify how severe the degree of damage to human organs. For this purpose, patients are referred by ultrasound, ECG and other diagnostic-type procedures.
There are several options that help alleviate the condition of a sick person. The first is the so-called bleeding. Also, some experts prefer to resort to selective removal of certain red blood cells from the blood. This procedure is performed using very expensive equipment. Cytostatics and alpha interferon can also be used.
If we talk about drug treatment, then in this case most often used:
- "Allopurinol". This drug helps to significantly reduce the amount of uric acid in the blood.This improves kidney function and eliminates severe pain in the limbs of a person.
- Antiplatelet and anticoagulants. These drugs are necessary in order to normalize the processes of microcirculation. This can avoid the formation of blood clots.
- Antihistamines. They help a person cope with itchy skin.
Traditional medicine and proper nutrition
First of all, it is worth noting that in order to get rid of polycythemia, it is very important to eat and take care that a person does not overload himself physically. If we are talking about the very beginning of the development of pathology, the patient is assigned table number 15. However, there are some reservations. First of all, the patient should not eat those foods that can increase blood flow and blood formation, so you need to abandon the use of the liver. It is necessary to use dairy and vegetable products.
If the patient's condition is characterized by the second stage of pathology, then table No. 6 is assigned to him. A similar diet is recommended for gout. In this case, from your diet you must completely eliminate meat and fish dishes.It is also necessary to abandon legumes and sorrel.
After the patient is discharged from the hospital, he must carefully monitor their health and adhere to all the recommendations of the doctor.
If we talk about national treatment, almost all patients are interested in this issue. It is necessary to understand that this pathology develops for many years, accordingly, it will be problematic to choose the appropriate treatment with herbs. Even if the symptomatology of the pathology has subsided, this does not mean that the patient is completely cured. He may still face exacerbations of the disease. Unfortunately, with the help of herbs you can only relieve pain or dull it. However, the full recovery in this case is not a question.
First of all, you need to talk with your doctor, and only then think about the popular methods of treatment. If the doctor agrees to additional methods of therapy, then you need to remember that we are talking about blood disease.
The network can find a huge number of recipes that will help increase hemoglobin levels. However, this does not mean that these recommendations are suitable for dealing with polycythemia. Erythremia (Vaquez disease) is not so easily treatable with natural remedies.Although doctors are not against traditional medicine, when it comes to polycythemia, almost everyone agrees that in this case it is impossible to choose a complex of medicinal herbs. The course of pathology affects the work of the bone marrow and affects the circulatory system. It is necessary to objectively evaluate all the possibilities of natural products.
However, to improve their condition, some resort to recipes for blood thinning. For example, you can brew a spoonful of clover grass in a glass of boiling water. After the mixture has cooled, strain it through gauze. The finished medicine is taken three times a day, approximately 80-100 ml. The course of such treatment should not be more than one month. After that, you need to take a break.
Also, many use dry or fresh cranberries. Two spoons of natural product poured a glass of boiling water. After that, you need to cover the container and wait 20-30 minutes until the infusion is infused. After that, the acidic juice can be diluted with honey or plain sugar. The main advantage of this method is that cranberries can be drunk in any quantity, if the patient does not have any allergies.
If we are talking about this pathology, then you should not immediately draw an analogy with cancer tumors. Vequez's disease is well treatable. However, therapeutic measures should not be taken at the last stage of the disease. The good news is that the disease develops for a very long time. During this time, a person is guaranteed at least once to be examined by a doctor who will pay attention to blood tests.
However, if untreated, the patient is likely to develop complications. For example, some patients suffer from ischemia, pulmonary thromboembolism, cirrhosis, and many other incurable pathologies that can lead to death. Therefore, we should not be afraid of visits to the doctor, because the time to identify the disease is much easier and faster to cure.
Although there is a high probability of complete recovery, in some situations this pathology returns.
Information in conclusion
There is also relative erythremia. This pathology has nothing to do with true polycythemia, so do not confuse these two ailments. The relative form of the disease most often develops against the background of somatic manifestations, in a completely different pattern. This pathology is much easier to treat.
Nevertheless, a healthy diet is important for any person, regardless of what he is sick. Therefore, it is important to keep track of those products that fall on the dining table and spend as much time as possible in the fresh air. Such universal preventive measures will help to protect against a huge number of diseases.